Competing interests in a lung cancer with metastasis to the pituitary gland: syndrome of inappropriate ADH secretion versus diabetes insipidus

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Competing interests in a lung cancer with metastasis to the pituitary gland: syndrome of inappropriate ADH secretion versus diabetes insipidus

Metastases to the pituitary gland are rare; cancers that most commonly metastasize to the pituitary are breast and lung cancers. No specific computed tomography or magnetic resonance imaging features reliably distinguish primary pituitary masses from metastases. A combination of a detailed clinical assessment together with specialist endocrine and neuroradiology support is essential to make the...

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MR of pituitary metastasis in a patient with diabetes insipidus.

We present a case of acute-onset diabetes insipidus in a 69-year-old man who had been treated for lung cancer. T1-weighted MR images showed a thickened pituitary stalk and absence of the normal high intensity of the posterior pituitary lobe. Dynamic imaging demonstrated poor enhancement in the posterior lobe, whereas the anterior lobe was strongly enhanced. Autopsy revealed that metastatic tumo...

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Syndrome of Inappropriate Antidiuretic Hormone Secretion Associated with Small Cells Lung Cancer with Bone Metastasis

SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION ASSOCIATED WITH SMALL CELLS LUNG CANCER WITH BONE METASTASIS (ABSTRACT): A patient with a bone metastasis developed a asymptomatic hyponatremia, with all features of the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH). The event was interpreted as a consequence of ADH release due to to primary cancer located in the lungs ...

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Occult pulmonary malignancy in syndrome of inappropriate ADH secretion with normal ADH levels.

Although the syndrome of inappropriate ADH secretion (SIADH) has many causes, principally pulmonary, central nervous system or neoplastic disease, and drugs, patients may present with SIADH in whom the etiology is not readily evident. We measured serum ADH levels in such an individual in both the eunatremic and water-loaded states and found levels to be undetectable despite failure to dilute th...

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Clinical guidelines for management of diabetes insipidus and syndrome of inappropriate antidiuretic hormone secretion after pituitary surgery.

Changes in water metabolism and regulation of vasopressin (AVP) or antidiuretic hormone (ADH) are common complications of pituitary surgery. The scarcity of studies comparing different treatment and monitoring strategies for these disorders and the lack of prior clinical guidelines makes it difficult to provide recommendations following a methodology based on grades of evidence. This study revi...

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ژورنال

عنوان ژورنال: Oxford Medical Case Reports

سال: 2016

ISSN: 2053-8855

DOI: 10.1093/omcr/omw044